Hexapeptide, last generation obtained by way of special synthesis, has the property to reduce the wrinkle depth. It inhibits the production of catecholamine and the formation of the SNARE complex, involved in stimulation of contreffect of facial muscles, blocks transmission of nerve impulses to facial muscles, relaxes facial muscles, smooths expression wrinkles - especially on forehead and around eyes. It prevents skin aging caused by repetitive movements of facial muscles due to excessive catecholamine production. By its effect, peptide similar to A-type botulinum toxin, but the result is achieved without facial muscle paralysis, avoiding the “mask” effect. It is included into the composition of “Lotum” cream.