(Melissa officinalis L) is lamiaceae family plant. The aboveground part of the plant is used for therapeutic purposes. It contains tannin, essential oil (citral, citronellal, geraniol, mircen, linalool), organic acids (caffeic, oleanolic, ursolic), bitterness, vitamin C, carotene, macro- and microelements. Melissa produces a sedative, antispasmodic, analgesic, hypotensive, diuretic, antiflatulent effect. And it also stimulates appetite, enhances activity of digestive glands, improves digestion, stops nausea and vomiting, produces a positive effect on heart activity. It is used for diseases of the nervous system, neuralgia, insomnia, migraine, functional gastrointestinal disorders, cardiovascular diseases, hypertensive disease,forlactation enhancement. Melissa is contraindicatedforpregnancy, massive arterial hypertension.